Right heart function during simulated altitude in patients with pulmonary arterial hypertension

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Right heart function during simulated altitude in patients with pulmonary arterial hypertension

OBJECTIVE Patients with pulmonary arterial hypertension (PAH) are often recommended supplemental oxygen for altitude travel due to the possible deleterious effects of hypoxia on pulmonary haemodynamics and right heart function. This includes commercial aircraft travel; however, the direct effects and potential risks are unknown. METHODS Doppler echocardiography and gas exchange measures were ...

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Right Atrial Function in Pulmonary Arterial Hypertension.

BACKGROUND Elevated right atrial (RA) pressure is an established prognostic measure in pulmonary arterial hypertension (PAH). However, little is known about perturbations in RA function in PAH. METHODS AND RESULTS Reservoir (RA longitudinal strain [RA LS]), conduit (RA early LS rate), and active (RA late LS rate) phases were assessed by 2D speckle tracking in 65 patients with PAH, 6-minute wa...

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Pulmonary function differences in patients with chronic right heart failure secondary to pulmonary arterial hypertension and chronic left heart failure

BACKGROUND Pulmonary abnormalities are found in both chronic heart failure (CHF) and pulmonary arterial hypertension (PAH). The differences of pulmonary function in chronic left heart failure and chronic right heart failure are not fully understood. MATERIAL AND METHODS We evaluated 120 patients with stable CHF (60 with chronic left heart failure and 60 with chronic right heart failure). All ...

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Right Heart Adaptation to Pulmonary Arterial€Hypertension

From the *Departm the Netherlands; y Stanford Universi Pulmonary Divisio Texas; xPulmona University Hospit University of Pe Cardiovascular D #Department of P Brussels, Belgium; Critical Care Med nessee; yyThe Dav Hypertension, Div UCLA Medical C Group, Centre de mologie de Québ Pulmonary Circul Medical Education Care Medicine an wealth University, more, Maryland. Bayer, GlaxoSmith industry advi...

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Right ventricular diastolic impairment in patients with pulmonary arterial hypertension.

BACKGROUND The role of right ventricular (RV) diastolic stiffness in pulmonary arterial hypertension (PAH) is not well established. Therefore, we investigated the presence and possible underlying mechanisms of RV diastolic stiffness in PAH patients. METHODS AND RESULTS Single-beat RV pressure-volume analyses were performed in 21 PAH patients and 7 control subjects to study RV diastolic stiffn...

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ژورنال

عنوان ژورنال: Open Heart

سال: 2017

ISSN: 2053-3624

DOI: 10.1136/openhrt-2016-000532